5-Cholesten-3β,25-Diol 3-Sulfate Decreases Lipid Accumulation in Diet-Induced Nonalcoholic Fatty Liver Disease Mouse Model

Sterol regulatory element-binding protein-1c (SREBP-1c) increases lipogenesis at the transcriptional level, and its expression is upregulated by liver X receptor α (LXRα). The LXRα/SREBP-1c signaling may play a crucial role in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). We previous...

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Detalhes bibliográficos
Main Authors: Xu, Leyuan, Kim, Jin Koung, Bai, Qianming, Zhang, Xin, Kakiyama, Genta, Min, Hae-ki, Sanyal, Arun J., Pandak, William M., Ren, Shunlin
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583496/
https://ncbi.nlm.nih.gov/pubmed/23258548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.081505
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