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Liver-specific transgenic expression of cholesteryl ester hydrolase reduces atherosclerosis in Ldlr(−/−) mice

The liver plays a central role in the final elimination of cholesterol from the body either as bile acids or as free cholesterol (FC), and lipoprotein-derived cholesterol is the major source of total biliary cholesterol. HDL is the major lipoprotein responsible for removal and transport of cholester...

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Autori principali: Bie, Jinghua, Wang, Jing, Yuan, Quan, Kakiyama, Genta, Ghosh, Siddhartha S., Ghosh, Shobha
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966706/
https://ncbi.nlm.nih.gov/pubmed/24563511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M046524
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