Bile Acid 7α-Dehydroxylating Gut Bacteria Secrete Antibiotics that Inhibit Clostridium difficile: Role of Secondary Bile Acids

Clostridium scindens, biotransforms primary bile acids into secondary bile acids, is correlated with inhibition of Clostridium difficile growth in vivo. The aim of the current study was to determine how C. scindens regulates C. difficile growth in vitro and if these interactions might relate to the...

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Udgivet i:Cell Chem Biol
Main Authors: Kang, Jason D., Myers, Christopher J., Harris, Spencer C., Kakiyama, Genta, Lee, In-Kyoung, Yun, Bong-Sik, Matsuzaki, Keiichi, Furukawa, Megumi, Min, Hae-Ki, Bajaj, Jasmohan S., Zhou, Huiping, Hylemon, Phillip B.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338514/
https://ncbi.nlm.nih.gov/pubmed/30482679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.10.003
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