Functional Intestinal Bile Acid 7α-Dehydroxylation by Clostridium scindens Associated with Protection from Clostridium difficile Infection in a Gnotobiotic Mouse Model

Bile acids, important mediators of lipid absorption, also act as hormone-like regulators and as antimicrobial molecules. In all these functions their potency is modulated by a variety of chemical modifications catalyzed by bacteria of the healthy gut microbiota, generating a complex variety of secon...

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Veröffentlicht in:Front Cell Infect Microbiol
Hauptverfasser: Studer, Nicolas, Desharnais, Lyne, Beutler, Markus, Brugiroux, Sandrine, Terrazos, Miguel A., Menin, Laure, Schürch, Christian M., McCoy, Kathy D., Kuehne, Sarah A., Minton, Nigel P., Stecher, Bärbel, Bernier-Latmani, Rizlan, Hapfelmeier, Siegfried
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5168579/
https://ncbi.nlm.nih.gov/pubmed/28066726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2016.00191
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