The acidic pathway of bile acid synthesis: Not just an alternative pathway(☆)

por Pandak, William M., Kakiyama, Genta
Publicado no Liver Res (2019)

α(1)-Fetoprotein Transcription Factor (FTF)/Liver Receptor Homolog-1 (LRH-1) Is an Essential Lipogenic Regulator

por Xu, Zhumei, Ouyang, Lingli, Castillo-Olivares, Antonio del, Pandak, William M., Gil, Gregorio
Publicado em 2009

StAR overexpression decreases serum and tissue lipids in apolipoprotein E-deficient mice

por Ning, Yanxia, Xu, Leyuan, Ren, Shunlin, Pandak, William M., Chen, Sifeng, Yin, Lianhua
Publicado em 2009

Interactions between Bile Acids and Nuclear Receptors and Their Effects on Lipid Metabolism and Liver Diseases

por Wang, David Q.-H., Neuschwander-Tetri, Brent A., Portincasa, Piero, Pandak, William M.
Publicado em 2012

Bile acids as regulatory molecules

por Hylemon, Phillip B., Zhou, Huiping, Pandak, William M., Ren, Shunlin, Gil, Gregorio, Dent, Paul
Publicado em 2009

Sulfated Oxysterol, 25HC3S, is a Potent Regulator of Lipid Metabolism in Human Hepatocytes

por Ren, Shunlin, Li, Xiaobo, Rodriguez-Agudo, Daniel, Gil, Gregorio, Hylemon, Phillip, Pandak, William M.
Publicado em 2007

The StarD4 subfamily of steroidogenic acute regulatory-related lipid transfer (START) domain proteins: new players in cholesterol metabolism

por Calderon-Dominguez, Maria, Gil, Gregorio, Medina, Miguel Angel, Pandak, William M., Rodríguez-Agudo, Daniel
Publicado em 2014

High Glucose Induces Lipid Accumulation via 25-Hydroxycholesterol DNA-CpG Methylation

por Wang, Yaping, Chen, Lanming, Pandak, William M., Heuman, Douglas, Hylemon, Phillip B., Ren, Shunlin
Publicado no iScience (2020)

Cytosolic sulfotransferase 2B1b promotes hepatocyte proliferation gene expression in vivo and in vitro

por Zhang, Xin, Bai, Qianming, Xu, Leyuan, Kakiyama, Genta, Pandak, William M., Zhang, Zhigang, Ren, Shunlin
Publicado em 2012

Cholesterol metabolite, 5-cholesten-3beta, 25-diol 3-sulfate, promotes hepatic proliferation in mice

por Zhang, Xin, Bai, Qianming, Kakiyama, Genta, Xu, Leyuan, Kim, Jin Kyung, Pandak, William M., Ren, Shunlin
Publicado em 2012

ER stress increases StarD5 expression by stabilizing its mRNA and leads to relocalization of its protein from the nucleus to the membranes

por Rodriguez-Agudo, Daniel, Calderon-Dominguez, Maria, Medina, Miguel Angel, Ren, Shunlin, Gil, Gregorio, Pandak, William M.
Publicado em 2012

Intracellular cholesterol transporter StarD4 binds free cholesterol and increases cholesteryl ester formation

por Rodriguez-Agudo, Daniel, Ren, Shunlin, Wong, Eric, Marques, Dalila, Redford, Kaye, Gil, Gregorio, Hylemon, Phillip, Pandak, William M.
Publicado em 2008

Identification of Novel Regulatory Cholesterol Metabolite, 5-Cholesten, 3β,25-Diol, Disulfate

por Ren, Shunlin, Kim, Jin Koung, Kakiyama, Genta, Rodriguez-Agudo, Daniel, Pandak, William M., Min, Hae-Ki, Ning, Yanxia
Publicado em 2014

Overexpression of mitochondrial cholesterol delivery protein, StAR, decreases intracellular lipids and inflammatory factors secretion in macrophages

por Ning, Yanxia, Bai, Qianming, Lu, Hong, Li, Xiaobo, Pandak, William M., Zhao, Fengdi, Chen, Sifeng, Ren, Shunlin, Yin, Lianhua
Publicado em 2008

25-Hydroxycholesterol-3-sulfate regulates macrophage lipid metabolism via the LXR/SREBP-1 signaling pathway

por Ma, Yongjie, Xu, Leyuan, Rodriguez-Agudo, Daniel, Li, Xiaobo, Heuman, Douglas M., Hylemon, Phillip B., Pandak, William M., Ren, Shunlin
Publicado em 2008

Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells

por Bai, Qianming, Xu, Leyuan, Kakiyama, Genta, Runge-Morris, Melissa Ann, Hylemon, Phillip B., Yin, Lianhua, Pandak, William M., Ren, Shunlin
Publicado em 2010

A simple and accurate HPLC method for fecal bile acid profile in healthy and cirrhotic subjects: validation by GC-MS and LC-MS

por Kakiyama, Genta, Muto, Akina, Takei, Hajime, Nittono, Hiroshi, Murai, Tsuyoshi, Kurosawa, Takao, Hofmann, Alan F., Pandak, William M., Bajaj, Jasmohan S.
Publicado em 2014

Berberine Inhibits HIV Protease Inhibitor-Induced Inflammatory Response by Modulating ER Stress Signaling Pathways in Murine Macrophages

por Zha, Weibin, Liang, Guang, Xiao, Jian, Studer, Elaine J., Hylemon, Phillip B., Pandak,, William M., Wang, Guangji, Li, Xiaokun, Zhou, Huiping
Publicado em 2010

Oxysterol Sulfation by SULT2B1b Suppresses LXR/SREBP-1c Signaling Pathway and Reduces Serum and Hepatic Lipids in Mouse Models of NAFLD

por Bai, Qianming, Zhang, Xin, Xu, Leyuan, Kakiyama, Genta, Heuman, Douglas, Sanyal, Arun, Pandak, William M., Yin, Lianhua, Xie, Wen, Ren, Shunlin
Publicado em 2012

Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro...

por Sharon, Chetna, Baranwal, Somesh, Patel, Nirmita J., Rodriguez-Agudo, Daniel, Pandak, William M., Majumdar, Adhip PN, Krystal, Geoffrey, Patel, Bhaumik B.
Publicado no Oncotarget (2015)