Deciphering the pathogenic consequences of chromosomal aberrations in human genetic disease

Por Kloosterman, Wigard P, Hochstenbach, Ron
Publicado no Mol Cytogenet (2014)

Substrate requirements for let-7 function in the developing zebrafish embryo

Por Kloosterman, Wigard P., Wienholds, Erno, Ketting, René F., Plasterk, Ronald H.A.
Publicado em 2004

Substrate requirements for let-7 function in the developing zebrafish embryo

Por Kloosterman, Wigard P., Wienholds, Erno, Ketting, René F., Plasterk, Ronald H.A.
Publicado no Nucleic Acids Res (2016)

RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain

Por NELSON, PETER T., BALDWIN, DON A., KLOOSTERMAN, WIGARD P., KAUPPINEN, SAKARI, PLASTERK, RONALD H.A., MOURELATOS, ZISSIMOS
Publicado em 2006

Targeted Inhibition of miRNA Maturation with Morpholinos Reveals a Role for miR-375 in Pancreatic Islet Development

Por Kloosterman, Wigard P, Lagendijk, Anne K, Ketting, René F, Moulton, Jon D, Plasterk, Ronald H. A
Publicado em 2007

MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system

Por Kapsimali, Marika, Kloosterman, Wigard P, de Bruijn, Ewart, Rosa, Frederic, Plasterk, Ronald HA, Wilson, Stephen W
Publicado em 2007

miR-451 regulates zebrafish erythroid maturation in vivo via its target gata2

Por Pase, Luke, Layton, Judith E., Kloosterman, Wigard P., Carradice, Duncan, Waterhouse, Peter M., Lieschke, Graham J.
Publicado em 2009

The presence of extra chromosomes leads to genomic instability

Por Passerini, Verena, Ozeri-Galai, Efrat, de Pagter, Mirjam S., Donnelly, Neysan, Schmalbrock, Sarah, Kloosterman, Wigard P., Kerem, Batsheva, Storchová, Zuzana
Publicado no Nat Commun (2016)

Differences in vertebrate microRNA expression

Por Ason, Brandon, Darnell, Diana K., Wittbrodt, Beate, Berezikov, Eugene, Kloosterman, Wigard P., Wittbrodt, Jochen, Antin, Parker B., Plasterk, Ronald H. A.
Publicado em 2006

Cloning and expression of new microRNAs from zebrafish

Por Kloosterman, Wigard P., Steiner, Florian A., Berezikov, Eugene, de Bruijn, Ewart, van de Belt, Jose, Verheul, Mark, Cuppen, Edwin, Plasterk, Ronald H.A.
Publicado em 2006

ViVar: A Comprehensive Platform for the Analysis and Visualization of Structural Genomic Variation

Por Sante, Tom, Vergult, Sarah, Volders, Pieter-Jan, Kloosterman, Wigard P., Trooskens, Geert, De Preter, Katleen, Dheedene, Annelies, Speleman, Frank, De Meyer, Tim, Menten, Björn
Publicado no PLoS One (2014)

Improving mammalian genome scaffolding using large insert mate-pair next-generation sequencing

Por van Heesch, Sebastiaan, Kloosterman, Wigard P, Lansu, Nico, Ruzius, Frans-Paul, Levandowsky, Elizabeth, Lee, Clarence C, Zhou, Shiguo, Goldstein, Steve, Schwartz, David C, Harkins, Timothy T, Guryev, Victor, Cuppen, Edwin
Publicado em 2013

Same-day genomic and epigenomic diagnosis of brain tumors using real-time nanopore sequencing

Por Euskirchen, Philipp, Bielle, Franck, Labreche, Karim, Kloosterman, Wigard P., Rosenberg, Shai, Daniau, Mailys, Schmitt, Charlotte, Masliah-Planchon, Julien, Bourdeaut, Franck, Dehais, Caroline, Marie, Yannick, Delattre, Jean-Yves, Idbaih, Ahmed
Publicado no Acta Neuropathol (2017)

Chromothripsis in Healthy Individuals Affects Multiple Protein-Coding Genes and Can Result in Severe Congenital Abnormalities in Offspring

Por de Pagter, Mirjam S., van Roosmalen, Markus J., Baas, Annette F., Renkens, Ivo, Duran, Karen J., van Binsbergen, Ellen, Tavakoli-Yaraki, Masoumeh, Hochstenbach, Ron, van der Veken, Lars T., Cuppen, Edwin, Kloosterman, Wigard P.
Publicado no Am J Hum Genet (2015)

Chromosomal instability, tolerance of mitotic errors and multidrug resistance are promoted by tetraploidization in human cells

Por Kuznetsova, Anastasia Y, Seget, Katarzyna, Moeller, Giuliana K, de Pagter, Mirjam S., de Roos, Jeroen A D M, Dürrbaum, Milena, Kuffer, Christian, Müller, Stefan, Zaman, Guido J R, Kloosterman, Wigard P, Storchová, Zuzana
Publicado no Cell Cycle (2015)

A framework for the detection of de novo mutations in family-based sequencing data

Por Francioli, Laurent C, Cretu-Stancu, Mircea, Garimella, Kiran V, Fromer, Menachem, Kloosterman, Wigard P, Samocha, Kaitlin E, Neale, Benjamin M, Daly, Mark J, Banks, Eric, DePristo, Mark A, de Bakker, Paul IW
Publicado no Eur J Hum Genet (2017)

Mouse microRNA profiles determined with a new and sensitive cloning method

Por Takada, Shuji, Berezikov, Eugene, Yamashita, Yoshihiro, Lagos-Quintana, Mariana, Kloosterman, Wigard P., Enomoto, Munehiro, Hatanaka, Hisashi, Fujiwara, Shin-ichiro, Watanabe, Hideki, Soda, Manabu, Choi, Young Lim, Plasterk, Ronald H. A., Cuppen, Edwin, Mano, Hiroyuki
Publicado em 2006

Discovery of variants unmasked by hemizygous deletions

Por Hochstenbach, Ron, Poot, Martin, Nijman, Isaac J, Renkens, Ivo, Duran, Karen J, van'T Slot, Ruben, van Binsbergen, Ellen, van der Zwaag, Bert, Vogel, Maartje J, Terhal, Paulien A, Ploos van Amstel, Hans Kristian, Kloosterman, Wigard P, Cuppen, Edwin
Publicado em 2012

Joubert syndrome: genotyping a Northern European patient cohort

Por Kroes, Hester Y, Monroe, Glen R, van der Zwaag, Bert, Duran, Karen J, de Kovel, Carolien G, van Roosmalen, Mark J, Harakalova, Magdalena, Nijman, Ies J, Kloosterman, Wigard P, Giles, Rachel H, Knoers, Nine VAM, van Haaften, Gijs
Publicado no Eur J Hum Genet (2016)

Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer

Por Kloosterman, Wigard P, Hoogstraat, Marlous, Paling, Oscar, Tavakoli-Yaraki, Masoumeh, Renkens, Ivo, Vermaat, Joost S, van Roosmalen, Markus J, van Lieshout, Stef, Nijman, Isaac J, Roessingh, Wijnand, van 't Slot, Ruben, van de Belt, José, Guryev, Victor, Koudijs, Marco, Voest, Emile, Cuppen, Edwin
Publicado em 2011