miR-451 regulates zebrafish erythroid maturation in vivo via its target gata2

We demonstrate that in zebrafish, the microRNA miR-451 plays a crucial role in promoting erythroid maturation, in part via its target transcript gata2. Zebrafish miR-144 and miR-451 are processed from a single precursor transcript selectively expressed in erythrocytes. In contrast to other hematopoi...

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Detalhes bibliográficos
Main Authors: Pase, Luke, Layton, Judith E., Kloosterman, Wigard P., Carradice, Duncan, Waterhouse, Peter M., Lieschke, Graham J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647672/
https://ncbi.nlm.nih.gov/pubmed/18849488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-155812
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