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Dose-dependent regulation of primitive erythroid maturation and identity by the transcription factor Eklf

The primitive erythroid (EryP) lineage is the first to differentiate during mammalian embryogenesis. Eklf/Klf1 is a transcriptional regulator that is essential for definitive erythropoiesis in the fetal liver. Dissection of the role(s) of Eklf within the EryP compartment has been confounded by the s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Isern, Joan, Fraser, Stuart T., He, Zhiyong, Zhang, Hailan, Baron, Margaret H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981545/
https://ncbi.nlm.nih.gov/pubmed/20720183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-281196
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