Ligand-induced folding of the guanine-sensing riboswitch is controlled by a combined predetermined–induced fit mechanism

Por Ottink, Otmar M., Rampersad, Sumientra M., Tessari, Marco, Zaman, Guido J.R., Heus, Hans A., Wijmenga, Sybren S.
Publicado em 2007

Discovery of Novel Small Molecule Activators of β-Catenin Signaling

Por Verkaar, Folkert, van der Stelt, Mario, Blankesteijn, W. Matthijs, van der Doelen, Antoon A., Zaman, Guido J. R.
Publicado em 2011

Quantitative proteomic and phosphoproteomic comparison of human colon cancer DLD-1 cells differing in ploidy and chromosome stability

Por Viganó, Cristina, von Schubert, Conrad, Ahrné, Erik, Schmidt, Alexander, Lorber, Thomas, Bubendorf, Lukas, De Vetter, Judith R. F., Zaman, Guido J. R., Storchova, Zuzana, Nigg, Erich A.
Publicado no Mol Biol Cell (2018)

Chromosomal instability, tolerance of mitotic errors and multidrug resistance are promoted by tetraploidization in human cells

Por Kuznetsova, Anastasia Y, Seget, Katarzyna, Moeller, Giuliana K, de Pagter, Mirjam S., de Roos, Jeroen A D M, Dürrbaum, Milena, Kuffer, Christian, Müller, Stefan, Zaman, Guido J R, Kloosterman, Wigard P, Storchová, Zuzana
Publicado no Cell Cycle (2015)

Comparison of the Cancer Gene Targeting and Biochemical Selectivities of All Targeted Kinase Inhibitors Approved for Clinical Use

Por Uitdehaag, Joost C. M., de Roos, Jeroen A. D. M., van Doornmalen, Antoon M., Prinsen, Martine B. W., de Man, Jos, Tanizawa, Yoshinori, Kawase, Yusuke, Yoshino, Kohichiro, Buijsman, Rogier C., Zaman, Guido J. R.
Publicado em 2014

N-acetylated Proline–Glycine–Proline induced G-protein dependent chemotaxis of neutrophils is independent of CXCL8 release

Por Overbeek, Saskia A., Henricks, Paul A.J., Srienc, Anja I., Koelink, Pim J., de Kruijf, Petra, Lim, Herman D., Smit, Martine J., Zaman, Guido J.R., Garssen, Johan, Nijkamp, Frans P., Kraneveld, Aletta D., Folkerts, Gert
Publicado em 2011

Non-competitive antagonism and inverse agonism as mechanism of action of non-peptidergic antagonists at primate and rodent CXCR3 chemokine receptors

Por Verzijl, Dennis, Storelli, Stefania, Scholten, Danny, Bosch, Leontien, Reinhart, Todd A., Streblow, Daniel N., Tensen, Cornelis P., Fitzsimons, Carlos P., Zaman, Guido J.R., Pease, James E., de Esch, Iwan J.P., Smit, Martine J., Leurs, Rob
Publicado em 2008

β-Arrestin Recruitment and G Protein Signaling by the Atypical Human Chemokine Decoy Receptor CCX-CKR

Por Watts, Anne O., Verkaar, Folkert, van der Lee, Miranda M. C., Timmerman, Claudia A. W., Kuijer, Martien, van Offenbeek, Jody, van Lith, Lambertus H. C. J., Smit, Martine J., Leurs, Rob, Zaman, Guido J. R., Vischer, Henry F.
Publicado em 2013

Selective Targeting of CTNNB1-, KRAS- or MYC-Driven Cell Growth by Combinations of Existing Drugs

Por Uitdehaag, Joost C. M., de Roos, Jeroen A. D. M., van Doornmalen, Antoon M., Prinsen, Martine B. W., Spijkers-Hagelstein, Jill A. P., de Vetter, Judith R. F., de Man, Jos, Buijsman, Rogier C., Zaman, Guido J. R.
Publicado no PLoS One (2015)

Characterization and Optimization of a Red-Shifted Fluorescence Polarization ADP Detection Assay

Por Kleman-Leyer, Karen M., Klink, Tony A., Kopp, Andrew L., Westermeyer, Thane A., Koeff, Mark D., Larson, Brad R., Worzella, Tracy J., Pinchard, Cori A., van de Kar, Sebastianus A.T., Zaman, Guido J.R., Hornberg, Jorrit J., Lowery, Robert G.
Publicado em 2009

Stable aneuploid tumors cells are more sensitive to TTK inhibition than chromosomally unstable cell lines

Por Libouban, Marion A.A., de Roos, Jeroen A.D.M., Uitdehaag, Joost C.M., Willemsen-Seegers, Nicole, Mainardi, Sara, Dylus, Jelle, de Man, Jos, Tops, Bastiaan, Meijerink, Jules P.P., Storchová, Zuzana, Buijsman, Rogier C., Medema, René H., Zaman, Guido J.R.
Publicado no Oncotarget (2017)

IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study

Por Li, Yunlei, Buijs-Gladdines, Jessica G. C. A. M., Canté-Barrett, Kirsten, Stubbs, Andrew P., Vroegindeweij, Eric M., Smits, Willem K., van Marion, Ronald, Dinjens, Winand N. M., Horstmann, Martin, Kuiper, Roland P., Buijsman, Rogier C., Zaman, Guido J. R., van der Spek, Peter J., Pieters, Rob, Meijerink, Jules P. P.
Publicado no PLoS Med (2016)

Chemokine cooperativity is caused by competitive glycosaminoglycan binding

Por Verkaar, Folkert, van Offenbeek, Jody, van der Lee, Miranda M.C., van Lith, Lambertus H.C.J., Watts, Anne O., Rops, Angelique L.W.M.M., Aguilar, David C., Ziarek, Joshua J., van der Vlag, Johan, Handel, Tracy M., Volkman, Brian F., Proudfoot, Amanda E.I., Vischer, Henry F., Zaman, Guido J.R., Smit, Martine J.
Publicado em 2014