Induced Pluripotent Stem Cells from Polycystic Kidney Disease Patients: A Novel Tool to Model the Pathogenesis of Cystic Kidney Disease

ανά Hofherr, Alexis, Köttgen, Michael
Έκδοση 2013

Nobel Prize 2020 in Chemistry honors CRISPR: a tool for rewriting the code of life

ανά Westermann, Lukas, Neubauer, Björn, Köttgen, Michael
Τόπος έκδοσης Pflugers Arch (2020)

Targeted rescue of a polycystic kidney disease mutation by lysosomal inhibition

ανά Hofherr, Alexis, Wagner, Claudius J., Watnick, Terry, Köttgen, Michael
Τόπος έκδοσης Kidney Int (2016)

N-Glycosylation Determines the Abundance of the Transient Receptor Potential Channel TRPP2

ανά Hofherr, Alexis, Wagner, Claudius, Fedeles, Sorin, Somlo, Stefan, Köttgen, Michael
Έκδοση 2014

Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout

ανά Woodward, Owen M., Köttgen, Anna, Coresh, Josef, Boerwinkle, Eric, Guggino, William B., Köttgen, Michael
Έκδοση 2009

Drosophila Sperm Swim Backwards in the Female Reproductive Tract and Are Activated via TRPP2 Ion Channels

ανά Köttgen, Michael, Hofherr, Alexis, Li, Weizhe, Chu, Kristy, Cook, Stacey, Montell, Craig, Watnick, Terry
Έκδοση 2011

P2Y6 receptor mediates colonic NaCl secretion via differential activation of cAMP-mediated transport

ανά Köttgen, Michael, Löffler, Thomas, Jacobi, Christoph, Nitschke, Roland, Pavenstädt, Hermann, Schreiber, Rainer, Frische, Sebastian, Nielsen, Søren, Leipziger, Jens
Έκδοση 2003

TRPP2 channels regulate apoptosis through the Ca(2+) concentration in the endoplasmic reticulum

ανά Wegierski, Tomasz, Steffl, Daniel, Kopp, Christoph, Tauber, Robert, Buchholz, Björn, Nitschke, Roland, Kuehn, E Wolfgang, Walz, Gerd, Köttgen, Michael
Έκδοση 2009

Efficient genome editing of differentiated renal epithelial cells

ανά Hofherr, Alexis, Busch, Tilman, Huber, Nora, Nold, Andreas, Bohn, Albert, Viau, Amandine, Bienaimé, Frank, Kuehn, E. Wolfgang, Arnold, Sebastian J., Köttgen, Michael
Τόπος έκδοσης Pflugers Arch (2016)

Identification of pathological transcription in autosomal dominant polycystic kidney disease epithelia

ανά Friedrich, Sebastian, Müller, Hannah, Riesterer, Caroline, Schüller, Hannah, Friedrich, Katja, Wörner, Carlotta Leonie, Busch, Tilman, Viau, Amandine, Kuehn, E. Wolfgang, Köttgen, Michael, Hofherr, Alexis
Τόπος έκδοσης Sci Rep (2021)

Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules

ανά Woodward, Owen M., Tukaye, Deepali N., Cui, Jinming, Greenwell, Patrick, Constantoulakis, Leeza M., Parker, Benjamin S., Rao, Anjana, Köttgen, Michael, Maloney, Peter C., Guggino, William B.
Έκδοση 2013

Eomes cannot replace its paralog T-bet during expansion and differentiation of CD8 effector T cells

ανά Fixemer, Jonas, Hummel, Jonas F., Arnold, Frederic, Klose, Christoph S. N., Hofherr, Alexis, Weissert, Kristoffer, Kögl, Tamara, Köttgen, Michael, Arnold, Sebastian J., Aichele, Peter, Tanriver, Yakup
Τόπος έκδοσης PLoS Pathog (2020)

Phosphorylation by casein kinase 2 induces PACS-1 binding of nephrocystin and targeting to cilia

ανά Schermer, Bernhard, Höpker, Katja, Omran, Heymut, Ghenoiu, Cristina, Fliegauf, Manfred, Fekete, Andrea, Horvath, Judit, Köttgen, Michael, Hackl, Matthias, Zschiedrich, Stefan, Huber, Tobias B, Kramer-Zucker, Albrecht, Zentgraf, Hanswalter, Blaukat, Andree, Walz, Gerd, Benzing, Thomas
Έκδοση 2005

Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation

ανά Köttgen, Michael, Benzing, Thomas, Simmen, Thomas, Tauber, Robert, Buchholz, Björn, Feliciangeli, Sylvain, Huber, Tobias B, Schermer, Bernhard, Kramer-Zucker, Albrecht, Höpker, Katja, Simmen, Katia Carmine, Tschucke, Christoph Carl, Sandford, Richard, Kim, Emily, Thomas, Gary, Walz, Gerd
Έκδοση 2005

Primary cilia regulate mTORC1 activity and cell size through Lkb1

ανά Boehlke, Christopher, Kotsis, Fruzsina, Patel, Vishal, Braeg, Simone, Voelker, Henriette, Bredt, Saskia, Beyer, Theresa, Janusch, Heike, Hamann, Christoph, Gödel, Markus, Müller, Klaus, Herbst, Martin, Hornung, Miriam, Doerken, Mara, Köttgen, Michael, Nitschke, Roland, Igarashi, Peter, Walz, Gerd, Kuehn, E. Wolfgang
Έκδοση 2010

The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism

ανά Hofherr, Alexis, Seger, Claudia, Fitzpatrick, Fiona, Busch, Tilman, Michel, Elisabeth, Luan, Jingting, Osterried, Lea, Linden, Frieder, Kramer-Zucker, Albrecht, Wakimoto, Barbara, Schütze, Conny, Wiedemann, Nils, Artati, Anna, Adamski, Jerzy, Walz, Gerd, Kunji, Edmund R. S., Montell, Craig, Watnick, Terry, Köttgen, Michael
Τόπος έκδοσης PLoS Biol (2018)

TRPP2 and TRPV4 form a polymodal sensory channel complex

ανά Köttgen, Michael, Buchholz, Björn, Garcia-Gonzalez, Miguel A., Kotsis, Fruzsina, Fu, Xiao, Doerken, Mara, Boehlke, Christopher, Steffl, Daniel, Tauber, Robert, Wegierski, Tomasz, Nitschke, Roland, Suzuki, Makoto, Kramer-Zucker, Albrecht, Germino, Gregory G., Watnick, Terry, Prenen, Jean, Nilius, Bernd, Kuehn, E. Wolfgang, Walz, Gerd
Έκδοση 2008

Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans

ανά Schlosser, Pascal, Li, Yong, Sekula, Peggy, Raffler, Johannes, Grundner-Culemann, Franziska, Pietzner, Maik, Cheng, Yurong, Wuttke, Matthias, Steinbrenner, Inga, Schultheiss, Ulla T., Kotsis, Fruzsina, Kacprowski, Tim, Forer, Lukas, Hausknecht, Birgit, Ekici, Arif B., Nauck, Matthias, Völker, Uwe, Walz, Gerd, Oefner, Peter J., Kronenberg, Florian, Mohney, Robert P., Köttgen, Michael, Suhre, Karsten, Eckardt, Kai-Uwe, Kastenmüller, Gabi, Köttgen, Anna
Τόπος έκδοσης Nat Genet (2020)

Cilia‐localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney

ανά Viau, Amandine, Bienaimé, Frank, Lukas, Kamile, Todkar, Abhijeet P, Knoll, Manuel, Yakulov, Toma A, Hofherr, Alexis, Kretz, Oliver, Helmstädter, Martin, Reichardt, Wilfried, Braeg, Simone, Aschman, Tom, Merkle, Annette, Pfeifer, Dietmar, Dumit, Verónica I, Gubler, Marie‐Claire, Nitschke, Roland, Huber, Tobias B, Terzi, Fabiola, Dengjel, Jörn, Grahammer, Florian, Köttgen, Michael, Busch, Hauke, Boerries, Melanie, Walz, Gerd, Triantafyllopoulou, Antigoni, Kuehn, E Wolfgang
Τόπος έκδοσης EMBO J (2018)

Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele

ανά Tin, Adrienne, Woodward, Owen M., Kao, Wen Hong Linda, Liu, Ching-Ti, Lu, Xiaoning, Nalls, Michael A., Shriner, Daniel, Semmo, Mariam, Akylbekova, Ermeg L., Wyatt, Sharon B., Hwang, Shih-Jen, Yang, Qiong, Zonderman, Alan B., Adeyemo, Adebowale A., Palmer, Cameron, Meng, Yan, Reilly, Muredach, Shlipak, Michael G., Siscovick, David, Evans, Michele K., Rotimi, Charles N., Flessner, Michael F., Köttgen, Michael, Cupples, L. Adrienne, Fox, Caroline S., Köttgen, Anna
Έκδοση 2011