Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation

The trafficking of ion channels to the plasma membrane is tightly controlled to ensure the proper regulation of intracellular ion homeostasis and signal transduction. Mutations of polycystin-2, a member of the TRP family of cation channels, cause autosomal dominant polycystic kidney disease, a disor...

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Bibliografiske detaljer
Main Authors: Köttgen, Michael, Benzing, Thomas, Simmen, Thomas, Tauber, Robert, Buchholz, Björn, Feliciangeli, Sylvain, Huber, Tobias B, Schermer, Bernhard, Kramer-Zucker, Albrecht, Höpker, Katja, Simmen, Katia Carmine, Tschucke, Christoph Carl, Sandford, Richard, Kim, Emily, Thomas, Gary, Walz, Gerd
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC549624/
https://ncbi.nlm.nih.gov/pubmed/15692563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600566
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