Phosphorylation by casein kinase 2 induces PACS-1 binding of nephrocystin and targeting to cilia

Mutations in proteins localized to cilia and basal bodies have been implicated in a growing number of human diseases. Access of these proteins to the ciliary compartment requires targeting to the base of the cilia. However, the mechanisms involved in transport of cilia proteins to this transitional...

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Autori principali: Schermer, Bernhard, Höpker, Katja, Omran, Heymut, Ghenoiu, Cristina, Fliegauf, Manfred, Fekete, Andrea, Horvath, Judit, Köttgen, Michael, Hackl, Matthias, Zschiedrich, Stefan, Huber, Tobias B, Kramer-Zucker, Albrecht, Zentgraf, Hanswalter, Blaukat, Andree, Walz, Gerd, Benzing, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2005
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356326/
https://ncbi.nlm.nih.gov/pubmed/16308564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600885
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