Eomes cannot replace its paralog T-bet during expansion and differentiation of CD8 effector T cells

The two T-box transcription factors T-bet and Eomesodermin (Eomes) are important regulators of cytotoxic lymphocytes (CTLs), such as activated CD8 T cells, which are essential in the fight against intracellular pathogens and tumors. Both transcription factors share a great degree of homology based o...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Fixemer, Jonas, Hummel, Jonas F., Arnold, Frederic, Klose, Christoph S. N., Hofherr, Alexis, Weissert, Kristoffer, Kögl, Tamara, Köttgen, Michael, Arnold, Sebastian J., Aichele, Peter, Tanriver, Yakup
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546498/
https://ncbi.nlm.nih.gov/pubmed/32991634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008870
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