Single-cell RNA-sequencing identifies the developmental trajectory of C-Myc-dependent NK1.1(−) T-bet(+) intraepithelial lymphocyte precursors

Natural intraepithelial lymphocytes (IELs) are thymus-derived adaptive immune cells, which are important contributors to intestinal immune homeostasis. Similar to other innate-like T cells, they are induced in the thymus through high-avidity interaction that would otherwise lead to clonal deletion i...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Hummel, Jonas F., Zeis, Patrice, Ebert, Karolina, Fixemer, Jonas, Konrad, Philip, Schachtrup, Christian, Arnold, Sebastian J., Grün, Dominic, Tanriver, Yakup
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group US 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039806/
https://ncbi.nlm.nih.gov/pubmed/31712600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-019-0220-y
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