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T-Bet and Eomes Regulate the Balance between the Effector/Central Memory T Cells versus Memory Stem Like T Cells

Memory T cells are composed of effector, central, and memory stem cells. Previous studies have implicated that both T-bet and Eomes are involved in the generation of effector and central memory CD8 T cells. The exact role of these transcription factors in shaping the memory T cell pool is not well u...

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Autors principals: Li, Gang, Yang, Qianting, Zhu, Yibei, Wang, Hong-Rui, Chen, Xinchun, Zhang, Xueguang, Lu, Binfeng
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694876/
https://ncbi.nlm.nih.gov/pubmed/23826287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067401
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