Identification of pathological transcription in autosomal dominant polycystic kidney disease epithelia

Autosomal dominant polycystic kidney disease (ADPKD) affects more than 12 million people worldwide. Mutations in PKD1 and PKD2 cause cyst formation through unknown mechanisms. To unravel the pathogenic mechanisms in ADPKD, multiple studies have investigated transcriptional mis-regulation in cystic k...

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Publicado no:Sci Rep
Main Authors: Friedrich, Sebastian, Müller, Hannah, Riesterer, Caroline, Schüller, Hannah, Friedrich, Katja, Wörner, Carlotta Leonie, Busch, Tilman, Viau, Amandine, Kuehn, E. Wolfgang, Köttgen, Michael, Hofherr, Alexis
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302622/
https://ncbi.nlm.nih.gov/pubmed/34301992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94442-8
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