Primary cilia regulate mTORC1 activity and cell size through Lkb1

The mTOR pathway is the central regulator of cell size(1). External signals from growth factors and nutrients converge on the mTORC1 multi-protein complex to modulate downstream targets, but how the different inputs are integrated and translated into specific cellular responses is incompletely under...

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Bibliografiset tiedot
Päätekijät: Boehlke, Christopher, Kotsis, Fruzsina, Patel, Vishal, Braeg, Simone, Voelker, Henriette, Bredt, Saskia, Beyer, Theresa, Janusch, Heike, Hamann, Christoph, Gödel, Markus, Müller, Klaus, Herbst, Martin, Hornung, Miriam, Doerken, Mara, Köttgen, Michael, Nitschke, Roland, Igarashi, Peter, Walz, Gerd, Kuehn, E. Wolfgang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390256/
https://ncbi.nlm.nih.gov/pubmed/20972424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2117
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