A Cilia Independent Role of Ift88/Polaris during Cell Migration

Ift88 is a central component of the intraflagellar transport (Ift) complex B, essential for the building of cilia and flagella from single cell organisms to mammals. Loss of Ift88 results in the absence of cilia and causes left-right asymmetry defects, disordered Hedgehog signaling, and polycystic k...

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Bibliographic Details
Published in:PLoS One
Main Authors: Boehlke, Christopher, Janusch, Heike, Hamann, Christoph, Powelske, Christian, Mergen, Miriam, Herbst, Henriette, Kotsis, Fruzsina, Nitschke, Roland, Kuehn, E. Wolfgang
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605505/
https://ncbi.nlm.nih.gov/pubmed/26465598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140378
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