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A Cilia Independent Role of Ift88/Polaris during Cell Migration

Ift88 is a central component of the intraflagellar transport (Ift) complex B, essential for the building of cilia and flagella from single cell organisms to mammals. Loss of Ift88 results in the absence of cilia and causes left-right asymmetry defects, disordered Hedgehog signaling, and polycystic k...

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Pubblicato in:PLoS One
Autori principali: Boehlke, Christopher, Janusch, Heike, Hamann, Christoph, Powelske, Christian, Mergen, Miriam, Herbst, Henriette, Kotsis, Fruzsina, Nitschke, Roland, Kuehn, E. Wolfgang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605505/
https://ncbi.nlm.nih.gov/pubmed/26465598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140378
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