Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly

Cilia are microtubule-based organelles that assemble via intraflagellar transport (IFT) and function as signaling hubs on eukaryotic cells. IFT relies on molecular motors and IFT complexes that mediate the contacts with ciliary cargo. To elucidate the architecture of the IFT-B complex, we reconstitu...

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Bibliografiska uppgifter
Huvudupphovsmän: Taschner, Michael, Kotsis, Fruzsina, Braeuer, Philipp, Kuehn, E. Wolfgang, Lorentzen, Esben
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2014
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210449/
https://ncbi.nlm.nih.gov/pubmed/25349261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201408002
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