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Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly

Cilia are microtubule-based organelles that assemble via intraflagellar transport (IFT) and function as signaling hubs on eukaryotic cells. IFT relies on molecular motors and IFT complexes that mediate the contacts with ciliary cargo. To elucidate the architecture of the IFT-B complex, we reconstitu...

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Detalhes bibliográficos
Main Authors: Taschner, Michael, Kotsis, Fruzsina, Braeuer, Philipp, Kuehn, E. Wolfgang, Lorentzen, Esben
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210449/
https://ncbi.nlm.nih.gov/pubmed/25349261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201408002
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