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The ciliary flow sensor and polycystic kidney disease

Since the discovery that proteins mutated in different forms of polycystic kidney disease (PKD) are tightly associated with primary cilia, strong efforts have been made to define the role of this organelle in the pathogenesis of cyst formation. Cilia are filiform microtubular structures, anchored in...

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Bibliographic Details
Main Authors: Kotsis, Fruzsina, Boehlke, Christopher, Kuehn, E. Wolfgang
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588856/
https://ncbi.nlm.nih.gov/pubmed/23314319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfs524
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