Role of Interleukin 10 Transcriptional Regulation in Inflammation and Autoimmune Disease

Por Iyer, Shankar Subramanian, Cheng, Genhong
Publicado em 2012

Lipopolysaccharide-Mediated IL-10 Transcriptional Regulation Requires Sequential Induction of Type I IFNs and IL-27 in Macrophages

Por Iyer, Shankar Subramanian, Ghaffari, Amir Ali, Cheng, Genhong
Publicado em 2010

How colonization by microbiota in early life shapes the immune system

Por Gensollen, Thomas, Iyer, Shankar S., Kasper, Dennis L., Blumberg, Richard S.
Publicado no Science (2016)

Positive feedback regulation of type I interferon by the interferon-stimulated gene STING

Por Ma, Feng, Li, Bing, Yu, Yongxin, Iyer, Shankar S, Sun, Mingyu, Cheng, Genhong
Publicado no EMBO Rep (2015)

PolyI:C Suppresses Acetaminophen-Induced Hepatotoxicity Independent of Type I Interferons and Toll-Like Receptor 3

Por Ghaffari, Amir A., Chow, Edward K., Iyer, Shankar S., Deng, Jane C., Cheng, Genhong
Publicado em 2011

Regulation of MHC class I expression by Foxp3 and its effect on Treg cell function

Por Mu, Jie, Tai, Xuguang, Iyer, Shankar S., Weissman, Jocelyn D., Singer, Alfred, Singer, Dinah S.
Publicado em 2014

Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS

Por Ma, Feng, Li, Bing, Liu, Su-yang, Iyer, Shankar S, Yu, Yongxin, Wu, Aiping, Cheng, Genhong
Publicado no J Immunol (2015)

CD1d-Restricted pathways in hepatocytes control local natural killer T cell homeostasis and hepatic inflammation

Por Zeissig, Sebastian, Peuker, Kenneth, Iyer, Shankar, Gensollen, Thomas, Dougan, Stephanie K., Olszak, Torsten, Kaser, Arthur, Blumberg, Richard S.
Publicado no Proc Natl Acad Sci U S A (2017)

Three Novel Downstream Promoter Elements Regulate MHC Class I Promoter Activity in Mammalian Cells

Por Lee, Namhoon, Iyer, Shankar S., Mu, Jie, Weissman, Jocelyn D., Ohali, Anat, Howcroft, T. Kevin, Lewis, Brian A., Singer, Dinah S.
Publicado em 2010

Glia Maturation Factor and Mitochondrial Uncoupling Proteins 2 and 4 Expression in the Temporal Cortex of Alzheimer’s Disease Brain

Por Thangavel, Ramasamy, Kempuraj, Duraisamy, Zaheer, Smita, Raikwar, Sudhanshu, Ahmed, Mohammad E., Selvakumar, Govindhasamy Pushpavathi, Iyer, Shankar S., Zaheer, Asgar
Publicado no Front Aging Neurosci (2017)

Cross-talk Between Glia, Neurons and Mast Cells in Neuroinflammation Associated with Parkinson’s Disease

Por Kempuraj, Duraisamy, Selvakumar, Govindhasamy Pushpavathi, Zaheer, Smita, Thangavel, Ramasamy, Ahmed, Mohammad Ejaz, Raikwar, Sudhanshu, Iyer, Shankar, Zaheer, Asgar
Publicado no J Neuroimmune Pharmacol (2017)

Co-localization of Glia Maturation Factor with NLRP3 Inflammasome and Autophagosome Markers in Human Alzheimer’s Disease Brain

Por Ahmed, Mohammad Ejaz, Iyer, Shankar, Thangavel, Ramasamy, Kempuraj, Duraisamy, Selvakumar, Govindhasamy Pushpavathi, Raikwar, Sudhanshu P., Zaheer, Smita, Zaheer, Asgar
Publicado no J Alzheimers Dis (2017)

Mast Cell Activation in Brain Injury, Stress, and Post-traumatic Stress Disorder and Alzheimer's Disease Pathogenesis

Por Kempuraj, Duraisamy, Selvakumar, Govindhasamy P., Thangavel, Ramasamy, Ahmed, Mohammad E., Zaheer, Smita, Raikwar, Sudhanshu P., Iyer, Shankar S., Bhagavan, Sachin M., Beladakere-Ramaswamy, Swathi, Zaheer, Asgar
Publicado no Front Neurosci (2017)

Increased susceptibility of spontaneously hypertensive rats to ventricular tachyarrhythmias in early hypertension

Por Nguyen, Thao P., Sovari, Ali A., Pezhouman, Arash, Iyer, Shankar, Cao, Hong, Ko, Christopher Y., Bapat, Aneesh, Vahdani, Nooshin, Ghanim, Mostafa, Fishbein, Michael C., Karagueuzian, Hrayr S.
Publicado no J Physiol (2016)

Brain and Peripheral Atypical Inflammatory Mediators Potentiate Neuroinflammation and Neurodegeneration

Por Kempuraj, Duraisamy, Thangavel, Ramasamy, Selvakumar, Govindhasamy P., Zaheer, Smita, Ahmed, Mohammad E., Raikwar, Sudhanshu P., Zahoor, Haris, Saeed, Daniyal, Natteru, Prashant A., Iyer, Shankar, Zaheer, Asgar
Publicado no Front Cell Neurosci (2017)

Co-expression of Glia Maturation Factor and Apolipoprotein E4 in Alzheimer’s Disease Brain

Por Thangavel, Ramasamy, Bhagavan, Sachin M., Ramaswamy, Swathi Beladakere, Surpur, Spurthi, Kempuraj, Duraisamy, Zaheer, Smita, Raikwar, Sudhanshu, Ahmed, Mohammad E., Selvakumar, Govindhasamy Pushpavathi, Iyer, Shankar S., Zaheer, Asgar
Publicado no J Alzheimers Dis (2018)

The Nalp3 inflammasome is essential for the development of silicosis

Por Cassel, Suzanne L., Eisenbarth, Stephanie C., Iyer, Shankar S., Sadler, Jeffrey J., Colegio, Oscar R., Tephly, Linda A., Carter, A. Brent, Rothman, Paul B., Flavell, Richard A., Sutterwala, Fayyaz S.
Publicado em 2008

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

Por Iyer, Shankar S., Pulskens, Wilco P., Sadler, Jeffrey J., Butter, Loes M., Teske, Gwendoline J., Ulland, Tyler K., Eisenbarth, Stephanie C., Florquin, Sandrine, Flavell, Richard A., Leemans, Jaklien C., Sutterwala, Fayyaz S.
Publicado em 2009

DDX41 recognizes bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response

Por Parvatiyar, Kislay, Zhang, Zhiqiang, Teles, Rosane M, Ouyang, Songying, Jiang, Yan, Iyer, Shankar S, Zaver, Shivam A, Schenk, Mirjam, Zeng, Shang, Zhong, Wenwan, Liu, Zhi-Jie, Modlin, Robert L, Liu, Yongjun, Cheng, Genhong
Publicado em 2012

Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation

Por Iyer, Shankar S., He, Qiong, Janczy, John R., Elliott, Eric I., Zhong, Zhenyu, Olivier, Alicia K., Sadler, Jeffrey J., Knepper-Adrian, Vickie, Han, Renzhi, Qiao, Liang, Eisenbarth, Stephanie C., Nauseef, William M., Cassel, Suzanne L., Sutterwala, Fayyaz S.
Publicado em 2013