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Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS
Rapid and robust induction of type I interferon (IFN-I) is a critical event in host antiviral innate immune response. It has been well demonstrated that cyclic GMP-AMP (cGAMP) synthase (cGAS) plays an important role in sensing cytosolic DNA and triggering stimulator of interferon genes (STING)-depen...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4324085/ https://ncbi.nlm.nih.gov/pubmed/25609843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402066 |
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