cGAS and Ifi204 Cooperate To Produce Type I IFNs in Response to Francisella Infection

Type I IFN production is an important host immune response against viral and bacterial infections. However, little is known about the ligands and corresponding host receptors that trigger type I IFN production during bacterial infections. We used a model intracellular pathogen, Francisella novicida,...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Storek, Kelly M., Gertsvolf, Nina A., Ohlson, Maikke B., Monack, Denise M.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2015
Assuntos:
Infectious Disease and Host Response
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367159/
https://ncbi.nlm.nih.gov/pubmed/25710914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402764
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