Priming and activation of inflammasome by canarypox virus vector ALVAC via the cGAS/IFI16-STING-Type I IFN pathway and AIM2 sensor

Viral vectors derived from different virus families, including poxvirus (canarypox virus vector ALVAC) and adenovirus (human Ad5 vector), have been widely used in vaccine development for a range of human diseases including HIV/AIDS. Less is known about mechanisms underlying host innate response to t...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Liu, Fengliang, Niu, Qingli, Fan, Xiuzhen, Liu, Connie, Zhang, Jie, Wei, Zhi, Hou, Wei, Kanneganti, Thirumala-Devi, Robb, Merlin L., Kim, Jerome H., Michael, Nelson L., Sun, Jiaren, Soong, Lynn, Hu, Haitao
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679316/
https://ncbi.nlm.nih.gov/pubmed/28947539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700698
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