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cGAS-STING pathway in cancer biotherapy

The activation of the cGAS-STING pathway has tremendous potential to improve anti-tumor immunity by generating type I interferons. In recent decades, we have witnessed that producing dsDNA upon various stimuli is an initiative factor, triggering the cGAS-SING pathway for a defensive host. The unders...

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Publicado en:Mol Cancer
Autores principales: Wang, Yang, Luo, Jingwen, Alu, Aqu, Han, Xuejiao, Wei, Yuquan, Wei, Xiawei
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472700/
https://ncbi.nlm.nih.gov/pubmed/32887628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01247-w
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