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Role of AIM2 inflammasome in inflammatory diseases, cancer and infection
AIM2 is a cytosolic innate immune receptor which recognizes double-stranded DNA (dsDNA) released during cellular perturbation and pathogenic assault. AIM2 recognition of dsDNA leads to the assembly of a large multiprotein oligomeric complex termed the inflammasome. This inflammasome assembly leads t...
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| Udgivet i: | Eur J Immunol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7015662/ https://ncbi.nlm.nih.gov/pubmed/31372985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201848070 |
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