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AIM2 inflammasome in infection, cancer and autoimmunity: role in DNA sensing, inflammation and innate immunity
Recognition of DNA by the cell is an important immunological signature that marks the initiation of an innate immune response. AIM2 is a cytoplasmic sensor that recognizes dsDNA of microbial or host origin. Upon binding to DNA, AIM2 assembles a multi-protein complex called the inflammasome, which dr...
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| 出版年: | Eur J Immunol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4758349/ https://ncbi.nlm.nih.gov/pubmed/26626159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545839 |
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