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Converging roles of caspases in inflammasome activation, cell death and innate immunity

Inflammatory and apoptotic caspases are central players in inflammation and apoptosis, respectively. However, recent studies have revealed that these caspases have functions beyond their established roles. In addition to mediating cleavage of the inflammasome-associated cytokines interleukin-1β (IL-...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Rev Immunol
Hauptverfasser: Man, Si Ming, Kanneganti, Thirumala-Devi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915362/
https://ncbi.nlm.nih.gov/pubmed/26655628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri.2015.7
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