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Converging roles of caspases in inflammasome activation, cell death and innate immunity

Inflammatory and apoptotic caspases are central players in inflammation and apoptosis, respectively. However, recent studies have revealed that these caspases have functions beyond their established roles. In addition to mediating cleavage of the inflammasome-associated cytokines interleukin-1β (IL-...

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Detalhes bibliográficos
Publicado no:Nat Rev Immunol
Main Authors: Man, Si Ming, Kanneganti, Thirumala-Devi
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915362/
https://ncbi.nlm.nih.gov/pubmed/26655628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri.2015.7
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