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The Nalp3 inflammasome is essential for the development of silicosis
Inhalation of crystalline silica and asbestos is known to cause the progressive pulmonary fibrotic disorders silicosis and asbestosis, respectively. Although alveolar macrophages are believed to initiate these inflammatory responses, the mechanism by which this occurs has been unclear. Here we show...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2449360/ https://ncbi.nlm.nih.gov/pubmed/18577586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803933105 |
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