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Sensing damage by the NLRP3 inflammasome
The NLRP3 inflammasome is activated in response to a variety of signals that are indicative of damage to the host including tissue damage, metabolic stress, and infection. Upon activation, the NLRP3 inflammasome serves as a platform for activation of the cysteine protease caspase-1, which leads to t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3170135/ https://ncbi.nlm.nih.gov/pubmed/21884174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2011.01043.x |
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