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Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

Aluminium adjuvants, typically referred to as ‘alum’, are the most commonly used adjuvants in human and animal vaccines worldwide, yet the mechanism underlying the stimulation of the immune system by alum remains unknown. Toll-like receptors are critical in sensing infections and are therefore commo...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Eisenbarth, Stephanie C., Colegio, Oscar R., O’Connor, William, Sutterwala, Fayyaz S., Flavell, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804622/
https://ncbi.nlm.nih.gov/pubmed/18496530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06939
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