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Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

Aluminium adjuvants, typically referred to as ‘alum’, are the most commonly used adjuvants in human and animal vaccines worldwide, yet the mechanism underlying the stimulation of the immune system by alum remains unknown. Toll-like receptors are critical in sensing infections and are therefore commo...

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Dades bibliogràfiques
Publicat a:Nature
Autors principals: Eisenbarth, Stephanie C., Colegio, Oscar R., O’Connor, William, Sutterwala, Fayyaz S., Flavell, Richard A.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804622/
https://ncbi.nlm.nih.gov/pubmed/18496530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06939
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