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PolyI:C Suppresses Acetaminophen-Induced Hepatotoxicity Independent of Type I Interferons and Toll-Like Receptor 3
Viral infections are often linked to altered drug metabolism in patients; however, the underlying molecular mechanisms remain unclear. Here, we describe a mechanism by which activation of anti-viral responses by the synthetic double stranded RNA ligand, polyinosinic-polycytidylic acid (polyI:C), lea...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103596/ https://ncbi.nlm.nih.gov/pubmed/21433044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24316 |
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