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Regulation of MHC class I expression by Foxp3 and its effect on Treg cell function
Expression of MHC class I molecules, which provide immune surveillance against intracellular pathogens, is higher on lymphoid cells than on any other cell types. In T cells, this is a result of activation of class I transcription by the T cell enhanceosome consisting of Runx1, CBFβ and LEF1. We now...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3952169/ https://ncbi.nlm.nih.gov/pubmed/24523508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302847 |
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