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Regulation of MHC class I expression by Foxp3 and its effect on Treg cell function

Expression of MHC class I molecules, which provide immune surveillance against intracellular pathogens, is higher on lymphoid cells than on any other cell types. In T cells, this is a result of activation of class I transcription by the T cell enhanceosome consisting of Runx1, CBFβ and LEF1. We now...

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Hlavní autoři: Mu, Jie, Tai, Xuguang, Iyer, Shankar S., Weissman, Jocelyn D., Singer, Alfred, Singer, Dinah S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952169/
https://ncbi.nlm.nih.gov/pubmed/24523508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302847
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