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In Vivo Expression of MHC Class I Genes Depends on the Presence of a Downstream Barrier Element

Regulation of MHC class I gene expression is critical to achieve proper immune surveillance. In this work, we identify elements downstream of the MHC class I promoter that are necessary for appropriate in vivo regulation: a novel barrier element that protects the MHC class I gene from silencing and...

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Detalhes bibliográficos
Main Authors: Cohen, Helit, Parekh, Palak, Sercan, Zeynep, Kotekar, Aparna, Weissman, Jocelyn D., Singer, Dinah S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727697/
https://ncbi.nlm.nih.gov/pubmed/19707598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006748
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