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CD1d-Restricted pathways in hepatocytes control local natural killer T cell homeostasis and hepatic inflammation

Invariant natural killer T (iNKT) cells recognize lipid antigens presented by CD1d and play a central role in regulating immunity and inflammation in peripheral tissues. However, the mechanisms which govern iNKT cell homeostasis after thymic emigration are incompletely understood. Here we demonstrat...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zeissig, Sebastian, Peuker, Kenneth, Iyer, Shankar, Gensollen, Thomas, Dougan, Stephanie K., Olszak, Torsten, Kaser, Arthur, Blumberg, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625893/
https://ncbi.nlm.nih.gov/pubmed/28893990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701428114
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