Safety and efficacy of nateglinide/metformin combination therapy in the treatment of type 2 diabetes

ανά Israel, Marc K, Istvan, Eva, Baron, Michelle A
Έκδοση 2008

Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis

ανά Istvan, Eva S., Palnitkar, Maya, Buchanan, Susan K., Deisenhofer, Johann
Έκδοση 2000

Malaria parasite plasmepsins: More than just plain old degradative pepsins

ανά Nasamu, Armiyaw S., Polino, Alexander J., Istvan, Eva S., Goldberg, Daniel E.
Τόπος έκδοσης J Biol Chem (2020)

Plasmodium falciparum ensures its amino acid supply with multiple acquisition pathways and redundant proteolytic enzyme systems

ανά Liu, Jun, Istvan, Eva S., Gluzman, Ilya Y., Gross, Julia, Goldberg, Daniel E.
Έκδοση 2006

Antimalarial Activity of Human Immunodeficiency Virus Type 1 Protease Inhibitors

ανά Parikh, Sunil, Gut, Jiri, Istvan, Eva, Goldberg, Daniel E., Havlir, Diane V., Rosenthal, Philip J.
Έκδοση 2005

Validation of isoleucine utilization targets in Plasmodium falciparum

ανά Istvan, Eva S., Dharia, Neekesh V., Bopp, Selina E., Gluzman, Ilya, Winzeler, Elizabeth A., Goldberg, Daniel E.
Έκδοση 2011

Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state

ανά Babbitt, Shalon E., Altenhofen, Lindsey, Cobbold, Simon A., Istvan, Eva S., Fennell, Clare, Doerig, Christian, Llinás, Manuel, Goldberg, Daniel E.
Έκδοση 2012

Esterase mutation is a mechanism of resistance to antimalarial compounds

ανά Istvan, Eva S., Mallari, Jeremy P., Corey, Victoria C., Dharia, Neekesh V., Marshall, Garland R., Winzeler, Elizabeth A., Goldberg, Daniel E.
Τόπος έκδοσης Nat Commun (2017)

Contacting domains segregate a lipid transporter from a solute transporter in the malarial host–parasite interface

ανά Garten, Matthias, Beck, Josh R., Roth, Robyn, Tenkova-Heuser, Tatyana, Heuser, John, Istvan, Eva S., Bleck, Christopher K. E., Goldberg, Daniel E., Zimmerberg, Joshua
Τόπος έκδοσης Nat Commun (2020)

Plasmodium Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis

ανά Istvan, Eva S, Das, Sudipta, Bhatnagar, Suyash, Beck, Josh R, Owen, Edward, Llinas, Manuel, Ganesan, Suresh M, Niles, Jacquin C, Winzeler, Elizabeth, Vaidya, Akhil B, Goldberg, Daniel E
Τόπος έκδοσης eLife (2019)

Combining Stage Specificity and Metabolomic Profiling to Advance Antimalarial Drug Discovery

ανά Murithi, James M., Owen, Edward S., Istvan, Eva S., Lee, Marcus C.S., Ottilie, Sabine, Chibale, Kelly, Goldberg, Daniel E., Winzeler, Elizabeth A., Llinás, Manuel, Fidock, David A., Vanaerschot, Manu
Τόπος έκδοσης Cell Chem Biol (2020)

PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum

ανά Rocamora, Frances, Gupta, Purva, Istvan, Eva S., Luth, Madeline R., Carpenter, Emma F., Kümpornsin, Krittikorn, Sasaki, Erika, Calla, Jaeson, Mittal, Nimisha, Carolino, Krypton, Owen, Edward, Llinás, Manuel, Ottilie, Sabine, Goldberg, Daniel E., Lee, Marcus C. S., Winzeler, Elizabeth A.
Τόπος έκδοσης ACS Infect Dis (2021)

MalDA, Accelerating Malaria Drug Discovery

ανά Yang, Tuo, Ottilie, Sabine, Istvan, Eva S., Godinez-Macias, Karla P., Lukens, Amanda K., Baragaña, Beatriz, Campo, Brice, Walpole, Chris, Niles, Jacquin C., Chibale, Kelly, Dechering, Koen J., Llinás, Manuel, Lee, Marcus C.S., Kato, Nobutaka, Wyllie, Susan, McNamara, Case W., Gamo, Francisco Javier, Burrows, Jeremy, Fidock, David A., Goldberg, Daniel E., Gilbert, Ian H., Wirth, Dyann F., Winzeler, Elizabeth A.
Τόπος έκδοσης Trends Parasitol (2021)

A broad analysis of resistance development in the malaria parasite

ανά Corey, Victoria C., Lukens, Amanda K., Istvan, Eva S., Lee, Marcus C. S., Franco, Virginia, Magistrado, Pamela, Coburn-Flynn, Olivia, Sakata-Kato, Tomoyo, Fuchs, Olivia, Gnädig, Nina F., Goldgof, Greg, Linares, Maria, Gomez-Lorenzo, Maria G., De Cózar, Cristina, Lafuente-Monasterio, Maria Jose, Prats, Sara, Meister, Stephan, Tanaseichuk, Olga, Wree, Melanie, Zhou, Yingyao, Willis, Paul A., Gamo, Francisco-Javier, Goldberg, Daniel E., Fidock, David A., Wirth, Dyann F., Winzeler, Elizabeth A.
Τόπος έκδοσης Nat Commun (2016)

Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box

ανά Reader, Janette, van der Watt, Mariëtte E., Taylor, Dale, Le Manach, Claire, Mittal, Nimisha, Ottilie, Sabine, Theron, Anjo, Moyo, Phanankosi, Erlank, Erica, Nardini, Luisa, Venter, Nelius, Lauterbach, Sonja, Bezuidenhout, Belinda, Horatscheck, Andre, van Heerden, Ashleigh, Spillman, Natalie J., Cowell, Anne N., Connacher, Jessica, Opperman, Daniel, Orchard, Lindsey M., Llinás, Manuel, Istvan, Eva S., Goldberg, Daniel E., Boyle, Grant A., Calvo, David, Mancama, Dalu, Coetzer, Theresa L., Winzeler, Elizabeth A., Duffy, James, Koekemoer, Lizette L., Basarab, Gregory, Chibale, Kelly, Birkholtz, Lyn-Marié
Τόπος έκδοσης Nat Commun (2021)

Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics

ανά Cowell, Annie N., Istvan, Eva S., Lukens, Amanda K., Gomez-Lorenzo, Maria G., Vanaerschot, Manu, Sakata-Kato, Tomoyo, Flannery, Erika L., Magistrado, Pamela, Owen, Edward, Abraham, Matthew, LaMonte, Gregory, Painter, Heather J., Williams, Roy M., Franco, Virginia, Linares, Maria, Arriaga, Ignacio, Bopp, Selina, Corey, Victoria C., Gnädig, Nina F., Coburn-Flynn, Olivia, Reimer, Christin, Gupta, Purva, Murithi, James M., Moura, Pedro A., Fuchs, Olivia, Sasaki, Erika, Kim, Sang W., Teng, Christine H., Wang, Lawrence T., Akidil, Aslı, Adjalley, Sophie, Willis, Paul A., Siege, Dionicio, Tanaseichuk, Olga, Zhong, Yang, Zhou, Yingyao, Llinás, Manuel, Ottilie, Sabine, Gamo, Francisco-Javier, Lee, Marcus C. S., Goldberg, Daniel E., Fidock, David A., Wirth, Dyann F., Winzeler, Elizabeth A.
Τόπος έκδοσης Science (2018)