Antimalarial Activity of Human Immunodeficiency Virus Type 1 Protease Inhibitors

Aspartic proteases play key roles in the biology of malaria parasites and human immunodeficiency virus type 1 (HIV-1). We tested the activity of seven HIV-1 protease inhibitors against cultured Plasmodium falciparum. All compounds inhibited the development of parasites at pharmacologically relevant...

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Bibliografiske detaljer
Main Authors: Parikh, Sunil, Gut, Jiri, Istvan, Eva, Goldberg, Daniel E., Havlir, Diane V., Rosenthal, Philip J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Susceptibility
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168637/
https://ncbi.nlm.nih.gov/pubmed/15980379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.7.2983-2985.2005
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