Antimalarial Activities of Novel Synthetic Cysteine Protease Inhibitors

Among promising new targets for antimalarial chemotherapy are the cysteine protease hemoglobinases falcipain-2 and falcipain-3. We evaluated the activities of synthetic peptidyl aldehyde and α-ketoamide cysteine protease inhibitors against these proteases, against cultured Plasmodium falciparum para...

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發表在:Antimicrob Agents Chemother
Main Authors: Lee, Belinda J., Singh, Ajay, Chiang, Peggy, Kemp, Scott J., Goldman, Erick A., Weinhouse, Michael I., Vlasuk, George P., Rosenthal, Philip J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2003
主題:
Susceptibility
在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296233/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14638488/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.12.3810-3814.2003
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