Antimalarial Activities of Novel Synthetic Cysteine Protease Inhibitors

Among promising new targets for antimalarial chemotherapy are the cysteine protease hemoglobinases falcipain-2 and falcipain-3. We evaluated the activities of synthetic peptidyl aldehyde and α-ketoamide cysteine protease inhibitors against these proteases, against cultured Plasmodium falciparum para...

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Main Authors: Lee, Belinda J., Singh, Ajay, Chiang, Peggy, Kemp, Scott J., Goldman, Erick A., Weinhouse, Michael I., Vlasuk, George P., Rosenthal, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Susceptibility
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC296233/
https://ncbi.nlm.nih.gov/pubmed/14638488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.12.3810-3814.2003
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