PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum

[Image: see text] In malaria, chemical genetics is a powerful method for assigning function to uncharacterized genes. MMV085203 and GNF-Pf-3600 are two structurally related napthoquinone phenotypic screening hits that kill both blood- and sexual-stage P. falciparum parasites in the low nanomolar to...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Rocamora, Frances, Gupta, Purva, Istvan, Eva S., Luth, Madeline R., Carpenter, Emma F., Kümpornsin, Krittikorn, Sasaki, Erika, Calla, Jaeson, Mittal, Nimisha, Carolino, Krypton, Owen, Edward, Llinás, Manuel, Ottilie, Sabine, Goldberg, Daniel E., Lee, Marcus C. S., Winzeler, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042660/
https://ncbi.nlm.nih.gov/pubmed/33715347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00676
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