Positive-unlabeled ensemble learning for kinase substrate prediction from dynamic phosphoproteomics data

por Yang, Pengyi, Humphrey, Sean J., James, David E., Yang, Yee Hwa, Jothi, Raja
Publicado en Bioinformatics (2016)

Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion

por Sacco, Francesca, Humphrey, Sean J., Cox, Jürgen, Mischnik, Marcel, Schulte, Anke, Klabunde, Thomas, Schäfer, Matthias, Mann, Matthias
Publicado en Nat Commun (2016)

Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2

por Humphrey, Sean J., Yang, Guang, Yang, Pengyi, Fazakerley, Daniel J., Stöckli, Jacqueline, Yang, Jean Y., James, David E.
Publicado 2013

KinasePA: Phosphoproteomics data annotation using hypothesis driven kinase perturbation analysis

por Yang, Pengyi, Patrick, Ellis, Humphrey, Sean J., Ghazanfar, Shila, James, David E., Jothi, Raja, Yang, Jean Yee Hwa
Publicado en Proteomics (2016)

TBC1D13 IS A RAB35 SPECIFIC GAP THAT PLAYS AN IMPORTANT ROLE IN GLUT4 TRAFFICKING IN ADIPOCYTES

por Davey, Jonathan R, Humphrey, Sean J, Junutula, Jagath R, Mishra, Ashwini K, Lambright, David G, James, David E, Stöckli, Jacqueline
Publicado 2012

Proteomic Analysis of Human Plasma during Intermittent Fasting

por Harney, Dylan J., Hutchison, Amy T., Hatchwell, Luke, Humphrey, Sean J., James, David E., Hocking, Samantha, Heilbronn, Leonie K., Larance, Mark
Publicado en J Proteome Res (2019)

Mechanism of Regulation of Intrachromatid Recombination and Long-Range Chromosome Interactions in Saccharomyces cerevisiae

por Zaman, Shamsu, Choudhury, Malay, Jiang, James C., Srivastava, Pankaj, Mohanty, Bidyut K., Danielson, Christopher, Humphrey, Sean J., Jazwinski, S. Michal, Bastia, Deepak
Publicado en Mol Cell Biol (2016)

RagC phosphorylation autoregulates mTOR complex 1

por Yang, Guang, Humphrey, Sean J, Murashige, Danielle S, Francis, Deanne, Wang, Qiao‐Ping, Cooke, Kristen C, Neely, G Gregory, James, David E
Publicado en EMBO J (2018)

Correction: Unraveling Kinase Activation Dynamics Using Kinase-Substrate Relationships from Temporal Large-Scale Phosphoproteomics Studies

por Domanova, Westa, Krycer, James R., Chaudhuri, Rima, Yang, Pengyi, Vafaee, Fatemeh, Fazakerley, Daniel J., Humphrey, Sean J., James, David E., Kuncic, Zdenka
Publicado en PLoS One (2017)

ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation

por Stöckli, Jacqueline, Zadoorian, Armella, Cooke, Kristen C., Deshpande, Vinita, Yau, Belinda, Herrmann, Gaia, Kebede, Melkam A., Humphrey, Sean J., James, David E.
Publicado en Mol Metab (2019)

Corrigendum to ‘ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation’ [Molecular Metabolism 25 (2019) p.83–94]

por Stöckli, Jacqueline, Zadoorian, Armella, Cooke, Kristen C., Deshpande, Vinita, Yau, Belinda, Herrmann, Gaia, Kebede, Melkam A., Humphrey, Sean J., James, David E.
Publicado en Mol Metab (2021)

Insulin Tolerance Test under Anaesthesia to Measure Tissue-specific Insulin-stimulated Glucose Disposal

por Fazakerley, Daniel J., Fritzen, Andreas M., Nelson, Marin E., Thorius, Ida H., Cooke, Kristen C., Humphrey, Sean J., Cooney, Gregory J., James, David E.
Publicado en Bio Protoc (2019)

PhosphOrtholog: a web-based tool for cross-species mapping of orthologous protein post-translational modifications

por Chaudhuri, Rima, Sadrieh, Arash, Hoffman, Nolan J., Parker, Benjamin L., Humphrey, Sean J., Stöckli, Jacqueline, Hill, Adam P., James, David E., Yang, Jean Yee Hwa
Publicado en BMC Genomics (2015)

A Two-Dimensional Metallacycle Cross-Linked Switchable Polymer for Fast and Highly Efficient Phosphorylated Peptide Enrichment

por Chen, Li-Jun, Humphrey, Sean J., Zhu, Jun-Long, Zhu, Fan-Fan, Wang, Xu-Qing, Wang, Xiang, Wen, Jin, Yang, Hai-Bo, Gale, Philip A.
Publicado en J Am Chem Soc (2021)

mTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in Adipocytes

por Minard, Annabel Y., Tan, Shi-Xiong, Yang, Pengyi, Fazakerley, Daniel J., Domanova, Westa, Parker, Benjamin L., Humphrey, Sean J., Jothi, Raja, Stöckli, Jacqueline, James, David E.
Publicado en Cell Rep (2016)

A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans

por Halova, Lenka, Cobley, David, Franz-Wachtel, Mirita, Wang, Tingting, Morrison, Kaitlin R., Krug, Karsten, Nalpas, Nicolas, Maček, Boris, Hagan, Iain M., Humphrey, Sean J., Petersen, Janni
Publicado en Open Biol (2021)

Multi-Omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency

por Yang, Pengyi, Humphrey, Sean J., Cinghu, Senthilkumar, Pathania, Rajneesh, Oldfield, Andrew J., Kumar, Dhirendra, Perera, Dinuka, Yang, Jean Y.H., James, David E., Mann, Matthias, Jothi, Raja
Publicado en Cell Syst (2019)

Transcriptional network dynamics during the progression of pluripotency revealed by integrative statistical learning

por Kim, Hani Jieun, Osteil, Pierre, Humphrey, Sean J, Cinghu, Senthilkumar, Oldfield, Andrew J, Patrick, Ellis, Wilkie, Emilie E, Peng, Guangdun, Suo, Shengbao, Jothi, Raja, Tam, Patrick P L, Yang, Pengyi
Publicado en Nucleic Acids Res (2020)

Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cells

por Recasens, Ariadna, Humphrey, Sean J., Ellis, Michael, Hoque, Monira, Abbassi, Ramzi H., Chen, Brianna, Longworth, Mitchell, Needham, Elise J., James, David E., Johns, Terrance G., Day, Bryan W., Kassiou, Michael, Yang, Pengyi, Munoz, Lenka
Publicado en Cell Death Discov (2021)

Hyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in Adipocytes

por Minard, Annabel Y., Wong, Martin K. L., Chaudhuri, Rima, Tan, Shi-Xiong, Humphrey, Sean J., Parker, Benjamin L., Yang, Jean Y., Laybutt, D. Ross, Cooney, Gregory J., Coster, Adelle C. F., Stöckli, Jacqueline, James, David E.
Publicado en J Biol Chem (2016)