Semi-Automated Analysis of Organelle Movement and Membrane Content: Understanding Rab-Motor Complex Transport Function

Por Hume, Alistair N, Wilson, Miranda S, Ushakov, Dmitry S, Ferenczi, Michael A, Seabra, Miguel C
Publicado em 2011

A Coiled-Coil Domain of Melanophilin Is Essential for Myosin Va Recruitment and Melanosome Transport in Melanocytes

Por Hume, Alistair N., Tarafder, Abul K., Ramalho, José S., Sviderskaya, Elena V., Seabra, Miguel C.
Publicado em 2006

Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells

Por Nightingale, Thomas D., Pattni, Krupa, Hume, Alistair N., Seabra, Miguel C., Cutler, Daniel F.
Publicado em 2009

A novel statin-mediated “prenylation block-and-release” assay provides insight into the membrane targeting mechanisms of small GTPases

Por Ali, Bassam R., Nouvel, Ian, Leung, Ka Fai, Hume, Alistair N., Seabra, Miguel C.
Publicado em 2010

Inefficient recruitment of kinesin-1 to melanosomes precludes it from facilitating their transport

Por Robinson, Christopher L., Evans, Richard D., Briggs, Deborah A., Ramalho, Jose S., Hume, Alistair N.
Publicado no J Cell Sci (2017)

A Role for Na(+),K(+)-ATPase α1 in Regulating Rab27a Localisation on Melanosomes

Por Booth, Antonia E. G., Tarafder, Abul K., Hume, Alistair N., Recchi, Chiara, Seabra, Miguel C.
Publicado em 2014

Correction: A Role for Na+,K+-ATPase α1 in Regulating Rab27a Localisation on Melanosomes

Por Booth, Antonia E. G., Tarafder, Abul K., Hume, Alistair N., Recchi, Chiara, Seabra, Miguel C.
Publicado no PLoS One (2016)

Rab27a Regulates the Peripheral Distribution of Melanosomes in Melanocytes

Por Hume, Alistair N., Collinson, Lucy M., Rapak, Andrzej, Gomes, Anita Q., Hopkins, Colin R., Seabra, Miguel C.
Publicado em 2001

A role for Rab27 in neutrophil chemotaxis and lung recruitment

Por Singh, Rajesh K, Furze, Rebecca C, Birrell, Mark A, Rankin, Sara M, Hume, Alistair N, Seabra, Miguel C
Publicado no BMC Cell Biol (2014)

Chromosomal mapping, gene structure and characterization of the human and murine <it>RAB27B</it> gene

Por Huxley Clare, Gregory-Evans Cheryl Y, McGuigan Amanda, Hume Alistair N, Tolmachova Tanya, Ramalho José S, Seabra Miguel C
Publicado em 2001-02-01

Chromosomal mapping, gene structure and characterization of the human and murine RAB27B gene

Por Ramalho, José S, Tolmachova, Tanya, Hume, Alistair N, McGuigan, Amanda, Gregory-Evans, Cheryl Y, Huxley, Clare, Seabra, Miguel C
Publicado em 2001

Myosin Va’s adaptor protein melanophilin enforces track selection on the microtubule and actin networks in vitro

Por Oberhofer, Angela, Spieler, Peter, Rosenfeld, Yuliya, Stepp, Willi L., Cleetus, Augustine, Hume, Alistair N., Mueller-Planitz, Felix, Ökten, Zeynep
Publicado no Proc Natl Acad Sci U S A (2017)

Membrane Targeting of Rab GTPases Is Influenced by the Prenylation Motif

Por Gomes, Anita Q., Ali, Bassam R., Ramalho, José S., Godfrey, Richard F., Barral, Duarte C., Hume, Alistair N., Seabra, Miguel C.
Publicado em 2003

Loss of Rab27 function results in abnormal lung epithelium structure in mice

Por Bolasco, Giulia, Tracey-White, Dhani C., Tolmachova, Tanya, Thorley, Andrew J., Tetley, Teresa D., Seabra, Miguel C., Hume, Alistair N.
Publicado em 2011

Rab27b regulates exocytosis of secretory vesicles in acinar epithelial cells from the lacrimal gland

Por Chiang, Lilian, Ngo, Julie, Schechter, Joel E., Karvar, Serhan, Tolmachova, Tanya, Seabra, Miguel C., Hume, Alistair N., Hamm-Alvarez, Sarah F.
Publicado em 2011

Rab27a-mediated protease release regulates neutrophil recruitment by allowing uropod detachment

Por Singh, Rajesh K., Liao, Wenjia, Tracey-White, Dhani, Recchi, Chiara, Tolmachova, Tanya, Rankin, Sara M., Hume, Alistair N., Seabra, Miguel C.
Publicado em 2012

Rab27a Targeting to Melanosomes Requires Nucleotide Exchange but Not Effector Binding

Por Tarafder, Abul K, Wasmeier, Christina, Figueiredo, Ana C, Booth, Antonia E G, Orihara, Asumi, Ramalho, Jose S, Hume, Alistair N, Seabra, Miguel C
Publicado em 2011

Rab27a Is Required for Regulated Secretion in Cytotoxic T Lymphocytes

Por Stinchcombe, Jane C., Barral, Duarte C., Mules, Emilie H., Booth, Sarah, Hume, Alistair N., Machesky, Laura M., Seabra, Miguel C., Griffiths, Gillian M.
Publicado em 2001

Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndrome

Por Barral, Duarte C., Ramalho, José S., Anders, Ross, Hume, Alistair N., Knapton, Holly J., Tolmachova, Tanya, Collinson, Lucy M., Goulding, David, Authi, Kalwant S., Seabra, Miguel C.
Publicado em 2002

Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndrome

Por Barral, Duarte C., Ramalho, José S., Anders, Ross, Hume, Alistair N., Knapton, Holly J., Tolmachova, Tanya, Collinson, Lucy M., Goulding, David, Authi, Kalwant S., Seabra, Miguel C.
Publicado em 2002