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Rab27b regulates exocytosis of secretory vesicles in acinar epithelial cells from the lacrimal gland

Tear proteins are supplied by the regulated fusion of secretory vesicles at the apical surface of lacrimal gland acinar cells, utilizing trafficking mechanisms largely yet uncharacterized. We investigated the role of Rab27b in the terminal release of these secretory vesicles. Confocal fluorescence m...

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Detalhes bibliográficos
Main Authors: Chiang, Lilian, Ngo, Julie, Schechter, Joel E., Karvar, Serhan, Tolmachova, Tanya, Seabra, Miguel C., Hume, Alistair N., Hamm-Alvarez, Sarah F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154548/
https://ncbi.nlm.nih.gov/pubmed/21525430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00355.2010
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