Loss of Rab27 function results in abnormal lung epithelium structure in mice

Rab27 small GTPases regulate secretion and movement of lysosome-related organelles such as T cell cytolytic granules and platelet-dense granules. Previous studies indicated that Rab27a and Rab27b are expressed in the murine lung suggesting that they regulate secretory processes in the lung. Consiste...

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Detalhes bibliográficos
Main Authors: Bolasco, Giulia, Tracey-White, Dhani C., Tolmachova, Tanya, Thorley, Andrew J., Tetley, Teresa D., Seabra, Miguel C., Hume, Alistair N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Protein and Vesicle Trafficking, Cytoskeleton
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063958/
https://ncbi.nlm.nih.gov/pubmed/21160031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00446.2010
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