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Membrane Targeting of Rab GTPases Is Influenced by the Prenylation Motif

Rab GTPases are regulators of membrane traffic. Rabs specifically associate with target membranes via the attachment of (usually) two geranylgeranyl groups in a reaction involving Rab escort protein and Rab geranylgeranyl transferase. In contrast, related GTPases are singly prenylated by CAAX prenyl...

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Detalhes bibliográficos
Main Authors: Gomes, Anita Q., Ali, Bassam R., Ramalho, José S., Godfrey, Richard F., Barral, Duarte C., Hume, Alistair N., Seabra, Miguel C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165084/
https://ncbi.nlm.nih.gov/pubmed/12802062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-10-0639
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