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Membrane Targeting of Rab GTPases Is Influenced by the Prenylation Motif

Rab GTPases are regulators of membrane traffic. Rabs specifically associate with target membranes via the attachment of (usually) two geranylgeranyl groups in a reaction involving Rab escort protein and Rab geranylgeranyl transferase. In contrast, related GTPases are singly prenylated by CAAX prenyl...

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Autors principals: Gomes, Anita Q., Ali, Bassam R., Ramalho, José S., Godfrey, Richard F., Barral, Duarte C., Hume, Alistair N., Seabra, Miguel C.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC165084/
https://ncbi.nlm.nih.gov/pubmed/12802062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-10-0639
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