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Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells
Endothelial cells contain cigar-shaped secretory organelles called Weibel-Palade bodies (WPBs) that play a crucial role in both hemostasis and the initiation of inflammation. The major cargo protein of WPBs is von Willebrand factor (VWF). In unstimulated cells, this protein is stored in a highly mul...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2686148/ https://ncbi.nlm.nih.gov/pubmed/19270261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-09-181206 |
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